I love my PICkit 2 but it refused to work on a new computer with Win10. There is a bit of information on the web, none of it very clear and concise whether this is a common problem along with some steps to try that did nothing for me.
Coccoliso on the Swordfish Basic forum came to the rescue with a re-compiled version of the PICkit 2 GUI that supports both the PICkit 2 and PICkit 3. It appears to work perfectly on my Win10 computer. You can find his revised version here. Before anybody gets upset about copyright issues, the GUI does allow for modification of the software:
You may use, copy, modify and distribute the Software for use with Microchip
products only. If you distribute the Software or its derivatives, the Software
must have this entire copyright and disclaimer notice prominently posted in a
location where end users will see it (e.g., installation program, program
headers, About Box, etc.)....
I know that the PIC's use a high voltage (beyond normal VCC) for programming, at least, like you said, the 18F series. I need to look into this because I have a ton of PIC parts in my bug trays that I gave up on because the special needs I thought they needed.
PICkit 2 on Win10 - A Solution
3 weeks 2 days ago #18058